One of the main objectives of psychotherapy is to address emotion dysregulation that causes pathological symptoms and distress in patients. Following psychodynamic theory, we propose that in humans, the combination of emotions plus conditioned anxiety due to traumatic attachment can lead to dysregulated affects. Likewise, defenses can generate and maintain dysregulated affects (altogether Dysregulated Affective States, DAS). We propose the Experiential-Dynamic Emotion Regulation methodology, a framework to understand emotion dysregulation by integrating scientific evidence coming from the fields of affective neuroscience (...) and Experiential-Dynamic Psychotherapy aimed at resolving DAS. This method and the techniques proposed can be integrated within other approaches. Similarities and differences with the Cognitive model of emotion regulation and cognitive-behavioral approaches are discussed within the paper. (shrink)

Western Australia, like Tasmania, can slip too easily off the map, a periphery on the periphery, its significance occluded by the hegemony of the eastern states of Australia. Yet Western Australia is core to Australia’s economy, not least through mining, and through its proximity to Asia. The West is itself connected more closely to region, in both the local and transnational senses. Its tradition of secessionist thinking indicates a kind of exceptionalist culture. This is a difference which begs for explanation. (...) This essay introduces some motifs and themes of this special issue of Thesis Eleven, entitled ‘Way Out West: Mapping Western Australia’. It locates the West in some recent historical, geographical and narrative context. It gestures toward the biography of its editors, Jon Stratton and Peter Beilharz, and their locations spread across the west and east of the continent. It calls for further scrutiny of these, and other antipodes. (shrink)

This book, first published in 1979, is composed of studies in a descending sequence from perfect rationality, through imperfect and problematical rationality, to irrationality. Specifically human rationality is characterized by its capacity to relate strategically to the future, in contrast to the myopic 'gradient climbing' of natural selection.

This paper analyses the methods of the International Agency for Research on Cancer (IARC) for evaluating the carcinogenicity of various agents. I identify two fundamental evidential principles that underpin these methods, which I call Evidential Proximity and Independence. I then show, by considering the 2018 evaluation of the carcinogenicity of styrene and styrene‐7,8‐oxide, that these principles have been implemented in a way that can lead to inconsistency. I suggest a way to resolve this problem: admit a general exception to Independence (...) and treat the implementation of Evidential Proximity more flexibly where this exception applies. I show that this suggestion is compatible with the general principles laid down in the 2019 version of IARC's methods guide, its Preamble to the Monographs. (shrink)

In the 1830s and 1840s, there was a decisive conflict between the Danish followers of Hegel and his opponents. The latter criticized Hegel’s philosophy for being overly abstract and having lost touch with reality. Kierkegaard is given credit for this criticism and for establishing a new philosophical direction that rejects abstraction and focuses on the concrete experience of the individual. The present article argues that there was nothing particularly new about Kierkegaard’s rejection of abstract philosophy and his attempt to emphasize (...) actuality and life. In fact, the conflict was wider and extended to many other Danish thinkers at the time who were critical of precisely this point in Hegel. (shrink)

Michel Foucault's involvement with politics, both as an individual and a writer, has been much commented upon but until now has not been systematically reviewed. This is the first major introductory study of Michel Foucault as a political thinker. Jonathon Simons explores the importance of the political in all areas of Foucault's work and life, including important material only recently made available and the implications of various revelations about his private life. Simons relates Foucault's work both to contemporary political thinkers (...) such as Michael Walzer, Charles Taylor and Jurgen Habermas, and to those challenging conventional political categories, especially people who write on feminist and gay theory, such as Judith Butler. Students of Foucault and of political and social theory, as well as those working in lesbian and gay theory, and feminist studies, will find this book essential. (shrink)

This chapter contains sections titled: Notes.

In this paper I argue that there is a significant but often overlooked metaphysical distinction to be made between contextualism and contrastivism. The orthodox view is that contrastivism is merely a form of contextualism. This is a mistake. The contextualist view is incompatible with certain naturalist claims about the metaphysical nature of concepts within whichever domain is being investigated, while the contrastivist view is compatible with these claims. So, choosing one view over the other will involve choosing to affirm or (...) deny a significant metaphysical claim. As such, a demarcation ought to be put in place between contextualism and contrastivism. (shrink)

The Recursive Bayesian Net (RBN) formalism was originally developed for modelling nested causal relationships. In this paper we argue that the formalism can also be applied to modelling the hierarchical structure of mechanisms. The resulting network contains quantitative information about probabilities, as well as qualitative information about mechanistic structure and causal relations. Since information about probabilities, mechanisms and causal relations is vital for prediction, explanation and control respectively, an RBN can be applied to all these tasks. We show in particular (...) how a simple two-level RBN can be used to model a mechanism in cancer science. The higher level of our model contains variables at the clinical level, while the lower level maps the structure of the cell's mechanism for apoptosis. (shrink)

Kyburg goes half-way towards objective Bayesianism. He accepts that frequencies constrain rational belief to an interval but stops short of isolating an optimal degree of belief within this interval. I examine the case for going the whole hog.

Metabolism is a set of chemical reactions, used by living organisms to process chemical compounds in order to take energy and eliminate toxic compounds, for example. Its processes are referred as metabolic pathways. Understanding metabolism is imperative to biology, toxicology and medicine, but the number and complexity of metabolic pathways makes this a difficult task. In our paper, we investigate the use of causal Bayesian networks to model the pathways of yeast saccharomyces cerevisiae metabolism: such a network can be used (...) to draw predictions about the levels of metabolites and enzymes in a particular specimen. We propose a two-stage methodology for causal networks, as follows. First construct a causal network from the network of metabolic pathways. The viability of this causal network depends on the validity of the causal Markov condition. If this condition fails, however, the principle of the common cause motivates the addition of a new causal arrow or a new `hidden' common cause to the network (stage 2 of the model formation process). Algorithms for adding arrows or hidden nodes have been developed separately in a number of papers, and in this paper we combine them, showing how the resulting procedure can be applied to the metabolic pathway problem. Our general approach was tested on neural cell morphology data and demonstrated noticeable improvements in both prediction and network accuracy. (shrink)

A traditional ethic of medicine asserts that physicians have special obligations to individual patients with whom they have a clinical relationship. Contemporary trends in US healthcare financing like bundled payments seem to threaten traditional conceptions of special obligations of individual physicians to individual patients because their population-based focus sets a tone that seems to emphasise responsibilities for groups of patients by groups of physicians in an organisation. Prior to undertaking a cogent debate about the fate and normative weight of special (...) obligations and a traditional ethic for contemporary healthcare, we need a deeper examination of what the traditional ethic of special obligations really means. Here we offer a conception of ‘doubly distributed’ special obligations. Physicians and similarly minded healing professionals abiding by a traditional ethic have always spread their devotion and attention across multiple patients and have shared responsibilities with physician and non-physician colleagues in much the same way devoted parents have frequently distributed their special obligations across multiple children and across multiple parents. By taking up the extended analogy of parent we argue that doubly distributing special obligations need not contradict the possibility of special obligations in restructured collective forms of healthcare delivery and financing. (shrink)

Debates over adaptationism can be clarified and partially resolved by careful consideration of the ‘grain’ at which evolutionary processes are described. The framework of ‘adaptive landscapes’ can be used to illustrate and facilitate this investigation. We argue that natural selection may have special status at an intermediate grain of analysis of evolutionary processes. The cases of sickle-cell disease and genomic imprinting are used as case studies.

Machamer, Darden and Craver: ‘Mechanisms are entities and activities organized such that they are productive of regular changes from start or set-up to finish or termination conditions.’ (Machamer, Darden and Craver 2000 p3.) Glennan: ‘A mechanism for a behavior is a complex system that produces that behavior by the interaction of a number of parts, where the interactions between parts can be characterized by direct, invariant, change-relating generalizations.’ (Glennan 2002b pS344.) Bechtel and Abrahamsen: ‘A mechanism is a structure performing a (...) function in virtue of its component parts, component operations, and their organization. The orchestrated functioning of the mechanism is responsible for one or more phenomena.’ (Bechtel and Abrahamsen 2005 p423.). (shrink)

Das Wissen um den Akt des Sterbens, der stets mit einer Form der Verwandlung oder Transformation des leiblichen Körpers in der Phase des „Danach“ einhergeht, beschert, so die These, der Menschheit seit jeher einen grenzenlosen Raum und kann womöglich als Ursprung jeglichen kulturellen und ästhetischen Ausdrucks gelten. Das „Danach“ bietet aufgrund seiner Dimension des „Nichtwissens“ eine größtmögliche Freiheit an Spekulationen. Der Artikel geht dieser Freiheit nach und beschreibt zunächst die vielfältigen religiösen und politischen Versuche, sie zugunsten der Stärkung eigener Macht (...) und Deutungshoheit zu beschränken. Sodann widmet er sich dem Potenzial künstlerischen, ästhetischen und kulturellen Schaffens, dem Nichtwissen einen Raum zu geben. Gegenwärtig stellt sich jedoch wie Frage, wie die „Freiheit der Kunst“ einerseits geschützt und andererseits ein verantwortungsvoller Umgang mit ihr garantiert werden kann. Dem Paradoxon zwischen ästhetischer Grenzenlosigkeit und gesellschaftlicher Einschränkung kann, so die These, allein das Wissen über das Nichtwissen des „Danach“ begegnen. Mehr noch, es vermag eine für heutige Herausforderungen vielversprechende Wirkmacht zu entfalten, die abschließend anhand von vier kulturpolitischen Prämissen vorgestellt wird. (shrink)

Die Grundprobleme der Logik ist ein unveränderter, hochwertiger Nachdruck der Originalausgabe aus dem Jahr 1895. Hansebooks ist Herausgeber von Literatur zu unterschiedlichen Themengebieten wie Forschung und Wissenschaft, Reisen und Expeditionen, Kochen und Ernährung, Medizin und weiteren Genres.Der Schwerpunkt des Verlages liegt auf dem Erhalt historischer Literatur.Viele Werke historischer Schriftsteller und Wissenschaftler sind heute nur noch als Antiquitäten erhältlich. Hansebooks verlegt diese Bücher neu und trägt damit zum Erhalt selten gewordener Literatur und historischem Wissen auch für die Zukunft bei.

Analytic theology is a thriving research program at the intersection of theology and analytic philosophy. Prior to Oliver Crisp and Michael Rea’s launch of “analytic theology” in 2009, the discipline functioned under the moniker “philosophical theology.” Considerable ink has been spilled on what is analytic theology in the past decade, and most recently by William Wood (2021). Some theologians (e.g., Abraham 2009) have argued that it is systematic theology while others (e.g., Coakley 2013) have been content to remain in a (...) family resemblance class rooted in philosophical theology. At the same time, analytic theology has welcomed Christian philosophers (e.g., Beall 2021) who have migrated into Christian doctrine via philosophy of religion. These philosophers are not systematic theologians, but, rather, philosophical theologians. This essay analyzes the relation between analytic theology, philosophical theology, and philosophy by examining their starting points and how they perceive and access truth, and then proposes a spectrum to graph their overlapping zones of research. I conclude that philosophical theology stands at the heart of the disciplines and thus remains an appropriate term for analytic theologians and Christian philosophers working somewhere in the vicinity of Jerusalem. (shrink)

The teratogenicity of the Zika virus was considered established in 2016, and is an interesting case because three different sets of causal criteria were used to assess teratogenicity. This paper appeals to the thesis of Russo and Williamson (2007) to devise an epistemological framework that can be used to compare and evaluate sets of causal criteria. The framework can also be used to decide when enough criteria are satisfied to establish causality. Arguably, the three sets of causal criteria considered here (...) offer only a rudimentary assessment of mechanistic studies, and some suggestions are made as to alternative ways to establish causality. (shrink)

After introducing a range of mechanistic theories of causality and some of the problems they face, I argue that while there is a decisive case against a purely mechanistic analysis, a viable theory of causality must incorporate mechanisms as an ingredient. I describe one way of providing an analysis of causality which reaps the rewards of the mechanistic approach without succumbing to its pitfalls.

The EBM+ programme is an attempt to improve the way in which present-day evidence-based medicine (EBM) assesses causal claims: according to EBM+, mechanistic studies should be scrutinised alongside association studies. This paper addresses two worries about EBM+: (i) that it is not feasible in practice, and (ii) that it is too malleable, i.e., its results depend on subjective choices that need to be made in order to implement the procedure. Several responses to these two worries are considered and evaluated. The (...) paper also discusses the question of whether we should have confidence in medical interventions, in the light of Stegenga's arguments for medical nihilism. (shrink)

This article examines the theoretical implications of the changing relationships between NGOs and businesses that have emerged as a response to the evolving agenda around CSR and sustainable development. In particular, it focuses upon examining whether greater engagement from non-governmental organisations (NGOs) in this area reflects a process of appropriation and co-optation of protest by the business community. To examine this process, the article considers two forms of appropriation—appropriation of language and appropriation via participation—as a basis for discussion. While co-optation (...) pressures are identified within both areas, the article argues that co-optation is identified almost as an inevitable outcome of engagement without significant consideration of the ability of movements to identify and respond to these processes. In identifying an alternative approach, the article utilises Mouffe’s framework of agonistic pluralism. Mouffe’s framework, it is argued, provides an understanding of the way in which agonistic relationships are emerging between NGOs and businesses while highlighting the continuance of conflict between parties struggling to influence the contested interpretations of responsible business. (shrink)